C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12N 15/12 (2006.01) C12P 19/34 (2006.01) C12Q 1/04 (2006.01)
Patent
CA 2596238
The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.
Brentnall Teresa A.
Bronner Mary Patricia
Chen Ru
Otey Carol A.
Poguegeile Katherine L.
Fetherstonhaugh & Co.
The Cleveland Clinic Foundation
The University Of North Carolina At Chapel Hill
University Of Pittsburgh - Of The Commonwealth System Of Higher
University Of Washington
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