Use of a chemotherapeutic agent in the preparation of a...

Details Use of a chemotherapeutic agent in the preparation of a... Use of a chemotherapeutic agent in the preparation of a...

A - Human Necessities

61

K

A61K 35/76 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2693623

Gemcitabine, irinotecan, doxorubicin and cisplatin are chemotherapeutic agents shown to inhibit the growth of an oncolytic vaccinia virus. As such, they can control viral titer- in a subject. These compounds i can be used for the treatment or amelioration of side affects associated with oncolytic virus therapy, or for controlling the oncolytic virus load in a subject.

L'invention concerne de la gemcitabine, de l'irinotécan, de la doxorubicine et du cisplatine, qui sont des agents chimiothérapeutiques connus pour empêcher la croissance d'un virus de la vaccine oncolytique. Ils peuvent réguler tel quel le titre viral chez un sujet. Ces composés peuvent être utilisés pour le traitement ou l'amélioration d'effets secondaires associés à une thérapie virale oncolytique, ou pour le contrôle de la charge virale oncolytique chez un sujet.

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