Use of seh inhibitors as analgesics

Details Use of seh inhibitors as analgesics Use of seh inhibitors as analgesics

A - Human Necessities

61

K

A61K 31/7088 (2006.01) A61K 31/336 (2006.01) A61P 17/02 (2006.01) A61P 23/02 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2619768

The present invention provides methods and compositions for relieving pain and itching, of promoting wound healing, of reducing sickness behavior and of reducing inflammatory bowel disease or acne lesions in a subject by the topical administration of an inhibitor of soluble epoxide hydrolase, or of a cis-epoxyeicosatrienoic acid ("EET"), or by both.

L'invention concerne des procédés et des compositions permettant de soulager la douleur et les prurits, de stimuler la cicatrisation, de diminuer le comportement pathologique et de réduire la maladie intestinale inflammatoire ou les lésions dues à l'acné chez un sujet par l'administration topique d'un inhibiteur de l'époxyde hydrolase soluble ou d'un acide cis-époxyeicosatriénoïque ("EET") ou des deux à la fois.

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