Novel antibodies against cancer target block tumor growth,...

Details Novel antibodies against cancer target block tumor growth,... Novel antibodies against cancer target block tumor growth,...

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C12N 5/16 (2006.01) C12Q 1/00 (2006.01) G01N 33/569 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2720025

The present invention provides antibodies that target the first-third domains of N-cadherein and the fourth domain of N-cadherin, for diagnosis and therapy of cancers related to N-cadherein. Methods of diagnosis and treatment utilizing these an-tibodies are also described.

La présente invention concerne des anticorps qui ciblent les premier-troisième domaines de la N-cadhérine et le quatrième domaine de la N-cadhérine, pour le diagnostic et la thérapie de cancers associés à la N-cadhérine. Linvention concerne également des procédés de diagnostic et de traitement utilisant ces anticorps.

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