Metal ion-binding mass markers for nucleic acids

Details Metal ion-binding mass markers for nucleic acids Metal ion-binding mass markers for nucleic acids

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2385962

Provided is a method for characterising an analyte, which method comprises: a) providing a compound in which the analyte is attached by a cleavable linker to a mass marker relatable to the analyte; b) cleaving the mass marker from the analyte; and c) identifying the mass marker, thereby characterising the analyte, wherein the mass marker comprises a metal ion-binding moiety.

L'invention porte sur un procédé destiné à caractériser un analyte et consistant à: (a) produire un composé dans lequel l'analyte est lié par un lieur clivable à un marqueur de masse pouvant être relié à l'analyte; (b) cliver le marqueur de masse à partir de l'analyte; et (c) identifier le marqueur de masse, ce qui permet de caractériser l'analyte. Ce marqueur de masse comprend une fraction se liant à l'ion métallique.

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