C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/06 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 5/18 (2006.01) C12N 15/13 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2291798
A monoclonal antibody capable of specifically and effectively recognizing hTERT protein which is the catalytic subunit of telomerase; a human chimeric antibody, a CDR transplantation antibody, a single-stranded antibody and a disulfide stabilizing antibody each containing the above monoclonal antibody; a method for detecting/quantitating hTERT protein by using these antibodies; and diagnostic methods, diagnostics and remedies for various diseases such as cancer in which telomerase participates.
L'invention concerne un anticorps monoclonal capable de reconnaître spécifiquement et efficacement une protéine hTERT qui est la sous-unité catalytique de télomérase, un anticorps chimère humain, un anticorps de transplantation CDR, un anticorps monocaténaire et un anticorps de stabilisation de disulfure contenant chacun l'anticorps monoclonal précité, une méthode de détection/quantification de protéine hTERT à l'aide de ces anticorps, ainsi que des méthodes de diagnostic, des diagnostics et des remèdes pour diverses maladies telles que le cancer dans lesquelles intervient la télomérase.
Anazawa Hideharu
Furuya Akiko
Hanai Nobuo
Mikuni Osamu
Shibata Kenji
Fetherstonhaugh & Co.
Kyowa Hakko Kogyo Co. Ltd.
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