Thiazole derivatives as active superoxide radical inhibitors

Details Thiazole derivatives as active superoxide radical inhibitors Thiazole derivatives as active superoxide radical inhibitors

C - Chemistry, Metallurgy

07

D

C07D 277/30 (2006.01) A61K 31/425 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/675 (2006.01) A61K 31/695 (2006.01) C07D 277/24 (2006.01) C07D 277/68 (2006.01) C07D 413/04 (2006.01) C07D 417/00 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01) C07D 453/02 (2006.01) C07D 513/04 (2006.01) C07F 7/10 (2006.01) C07F 9/547 (2006.01) C07F 9/6539 (2006.01) C07H 15/203 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2074933

A superoxide radical inhibitor containing, as an effective ingredient, an azole derivative represented by the general formula (1), Image [wherein R1 represents a phenyl group which may have 1-3 lower alkoxy groups as substituent(s) on the phenyl ring, a phenyl group having a lower alkylenedioxy group, or the like; R2 represents a hydrogen atom, a phenyl group, a halogen atom, a lower alkoxycarbonyl group, a lower alkyl group, an amino-lower alkyl group which may have a lower alkyl group as a substituent, a dihydrocarbostyril group, or the like; R3 represents a group of the formula, Image (R4B represents a hydroxyl group, a carboxy group, a lower alkenyl group or a lower alkyl group. m represents 0, 1 or 2); X represents a sulfur atom or an oxygen atom] or a salt thereof.

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