A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/04 (2006.01) A23K 1/16 (2006.01) A23L 1/315 (2006.01) A61K 9/48 (2006.01) A61K 38/05 (2006.01)
Patent
CA 2177075
A composition containing as the active principle an effective amount of aspartame for inhibiting the toxic effects of toxins, especially fungal toxins from the ochratoxin family, in both animals and humans. Aspartame controls the genotoxic effects, DNA adduct development and DNA methylation alteration caused by ochratoxins. Aspartame also controls nephrotoxicity as well as testicular diseases caused by said toxins.
L'invention concerne une composition contenant une quantité efficace d'aspartame en tant que principe actif destiné à combattre les effets toxiques causés chez l'animal comme chez l'homme par les toxines et plus particulièrement les toxines fongiques de la famille des orchratoxines. L'activité de l'aspartame se caractérise par la suppression des effets génotoxiques, apparitions d'adduits à l'ADN et modifications de la méthylation de l'ADN causés par les ochratoxines. L'aspartame contrecarre également la néphrotoxicité ainsi que les atteintes testiculaires causées par ces toxines.
Gharbi Abderrahmane
Messadek Jallal
Robic
LandOfFree
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