D-sorbitol dehydrogenase gene

Details D-sorbitol dehydrogenase gene D-sorbitol dehydrogenase gene

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C12N 1/21 (2006.01) C12N 9/04 (2006.01) C12P 19/02 (2006.01)

Patent

CA 2239802

A DNA comprising a nucleotide sequence which encodes a protein as defined by (a) or (b) and having sorbitol dehydrogenase activity: (a) a protein having the amino acid sequence from the position 1 to716 of the sequence described in SEQ ID NO: 2, or (b) a protein derived from the protein of (a) by substitution, deletion, insertion or addition of one or more amino acids in the amino acid sequence defined in (a), vectors, comprising such DNAs, hosts transformed by such vectors, a process for the preparation of such proteins and their use.

ADN renfermant une séquence de nucléotides codant une protéine, définie comme en A ou en B et possédant une activité de sorbitol-déshydrogénase : A) protéine renfermant la séquence d'acides aminés de la position 1 à 716 de la séquence décrite dans SEQ ID NO: 2; B) protéine dérivée de la protéine A par substitution, délétion, insertion ou addition d'un ou de plusieurs acides aminés dans la séquence d'acides aminés définie en A; vecteurs renfermant ce type d'ADN, hôtes transformés par ces vecteurs; méthode pour préparer ces protéines et leur utilisation.

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