Process for the preparation of quaternary n-alkyl morphinan...

Details Process for the preparation of quaternary n-alkyl morphinan... Process for the preparation of quaternary n-alkyl morphinan...

C - Chemistry, Metallurgy

07

D

C07D 489/02 (2006.01)

Patent

CA 2504262

A process for the preparation of a quaternary derivative of the morphinan alkaloid, the process comprising contacting a tertiary N-substituted morphinan alkaloid with an alkyl halide in an anhydrous solvent system, wherein the solvent system comprises an aprotic dipolar solvent with the aprotic dipolar solvent constituting at least 25 wt % of the solvent system. Exemplary compounds include: (see formula 1) (see formula 1A).

L'invention concerne une méthode de préparation d'un dérivé quaternaire de l'alcaloïde morphinique. La méthode consiste à placer un alcaloïde morphinique tertiaire N-substitué au contact d'un halogénure d'alkyle, dans un système de solvants anhydres dont au moins les 25 % en poids sont constitués d'un solvant bipolaire aprotique.

Affiliated with

Also associated with

Rating

Process for the preparation of quaternary n-alkyl morphinan... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of quaternary n-alkyl morphinan..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of quaternary n-alkyl morphinan... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1591714