C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01)
Patent
CA 2498495
The present invention is directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. This invention also relates to phenyl-aza-benzimidazole molecules that are cellular proliferation inhibitors and thus are useful as anticancer agents. This invention further relates to small molecules which suppress cytokines and leukocytes.
La présente invention se rapporte à des inhibiteurs de petites molécules de la réponse IgE aux allergènes que l'on utilise dans le traitement d'allergies et/ou de l'asthme ou d'autres maladies dans lesquelles l'IgE s'avère pathogène. L'invention se rapporte également à des molécules de phényl-aza-benzimidazole qui sont des inhibiteurs de la prolifération cellulaire et que l'on utilise, par conséquent, comme agents anticancéreux. L'invention se rapporte en outre à de petites molécules supprimant les cytokines et les leucocytes.
Richards Mark L.
Sinha Anjana
Sircar Jagadish C.
Thomas Richard J.
Avanir Pharmaceuticals
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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