Collagen material and its production process

B - Operations – Transporting – 32 – B

Patent

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B32B 9/02 (2006.01) A61L 27/24 (2006.01) A61L 27/40 (2006.01) A61L 31/06 (2006.01) A61L 31/12 (2006.01) A61F 2/00 (2006.01) C08H 1/06 (2006.01) C08L 89/06 (2006.01)

Patent

CA 2272905

A collagen material comprising a laminate of a multilayer structure of an ultrafine fibrous nonwoven fabric of collagen sandwiched between nonfibrillated collagen layers; a filamentous material comprising the collagen material; a process for producing the same; and a medical material comprising the collagen material, particularly a medical film substitute comprising the medical material. These materials are produced from collagen without using synthetic polymer material, have such a property as to permit suturing while maintaining the biochemical characteristics inherent in collagen. Further, the medical film substitute can be used as a material for making up for a defective portion of a biological membrane, such as a dura mater, heart sac, pleura, peritoneum, or chorion, poses no moral problem, can be stably supplied, have no fear of infection, causes no denaturation of cells, can control the degradation rate after application to the organism, and can promote the regeneration of a biological membrane.

L'invention concerne un matériau collagène comprenant un stratifié constitué d'une structure multicouche de textile non tissé fibreux et ultrafin de collagène, prise en sandwich entre des couches de collagène non fibrillées; un matériau filamenteux comprenant ledit matériau collagène; un procédé de production dudit matériau; et un matériau médical comprenant le matériau collagène, notamment un substitut de film médical comprenant ledit matériau médical. Ces matériaux sont produits à partir du collagène sans matériau polymère synthétique, présentent des propriétés permettant la suture et conservent simultanément les caractéristiques biochimiques propres au collagène. De plus, le substitut de film médical peut être utilisé comme matériau pour réparer une partie défectueuse d'une membrane biologique telle que la dure-mère, le péricarde, la plèvre, le chorion ou le péritoine, son utilisation ne pose aucun problème d'éthique. De plus, il peut être fourni de manière stable, ne pose pas de risque d'infection, ne provoque pas de dénaturation cellulaire, peut réguler la vitesse de dégradation après son application dans l'organisme et peut favoriser la régénération d'une membrane biologique.

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