Method of determining risk for cancer

Details Method of determining risk for cancer Method of determining risk for cancer

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2704118

A method of determining risk of cancer in a mammal is provided. The method includes analyzing the genomic DNA of the mammal and determining genomic CNV frequency or genomic structural variation. An increase in either CNV frequency or genomic structural variation in comparison to a baseline mean value is indicative of cancer.

La présente invention concerne un procédé de détermination du risque cancéreux chez un mammifère. Ledit procédé inclut l'analyse de l'ADN génomique dudit mammifère et la détermination de la fréquence CNV génomique ou de la variation structurale génomique. Une augmentation de la fréquence CNV ou de la variation structurale génomique par rapport à une valeur moyenne de référence indique un cancer.

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