A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/165 (2006.01) A61K 31/12 (2006.01) A61K 31/166 (2006.01) A61K 31/195 (2006.01) A61K 31/40 (2006.01) A61K 31/437 (2006.01) A61K 31/50 (2006.01)
Patent
CA 2169136
Invented is a method of treating a bone resorption disease in a subject which comprises administering to the subject a therapeutically effective amount of a compound which binds to a human src SH2 domain with a binding affinity greater than fifty-fold higher than the binding affinity with which the compound binds to a human lck SH2 domain and a human fyn SH2 domain, and, binds to a human hcp SH2 domain, a human Grb2 SH2 domain, a human SH-PTP2 SH2 domain and a human p85 SH2 domain with a binding affinity which is greater than fifty-fold lower than the binding affinity with which the compound binds to such src SH2 domain.
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
LandOfFree
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