Self-assembled, defective, non-self-propagating viral particles

C - Chemistry – Metallurgy – 12 – N

Patent

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167/130, 195/1.1

C12N 15/41 (2006.01) A61K 39/21 (2006.01) A61K 47/48 (2006.01) C07K 14/105 (2006.01) C07K 14/155 (2006.01) C12N 7/04 (2006.01) C12N 9/12 (2006.01) C12N 9/22 (2006.01) C12N 9/50 (2006.01) C12N 15/49 (2006.01) C12N 15/86 (2006.01) C12N 15/863 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2033175

Recombinant viral vectors which coexpress heterologous polypeptides capable of assembling into defective non-self-propagating viral particles are disclosed. The viral particles can be used as immunogens and for targeted delivery of drugs.

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