Quinolone derivatives

Details Quinolone derivatives Quinolone derivatives

C - Chemistry, Metallurgy

07

D

C07D 215/16 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 215/227 (2006.01) C07D 215/42 (2006.01) C07D 215/50 (2006.01) C07D 401/02 (2006.01) C07D 401/06 (2006.01) C07D 405/02 (2006.01) C07D 409/02 (2006.01) C07D 413/02 (2006.01) C07D 413/06 (2006.01) C07D 417/02 (2006.01)

Patent

CA 2122840

2122840 9311115 PCTABS00022 A class of 2-(1H)-quinolone derivatives, substituted at the 3-position by an optionally substituted aryl substituent, are selective non-competitive antagonists of NMDA receptors and/or are antagonists of AMPA receptors, and are therefore of utility in the treatment of conditions, such as neurodegenerative disorders, convulsions or schizophrenia, which require the administration of an NMDA and/or AMPA receptor antagonist.

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