Biofilm treatment

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4184 (2006.01) A61K 31/00 (2006.01) A61P 1/00 (2006.01) A61P 1/02 (2006.01) A61P 33/00 (2006.01) A61P 33/10 (2006.01)

Patent

CA 2693695

The invention provides a method of preventing, inhibiting or reducing a P. gingivalis biofilm in a subject comprising administering to the subject a pharmaceutical composition comprising an inhibiting agent of a polypeptide that reduces or inhibits biofilm formation and/or biofilm development. Also provided are compositions useful in the prevention, inhibition or treatment of periodontal disease or P. gingivalis infection.

L'invention propose un procédé de prévention, d'inhibition ou de réduction d'un biofilm de P. gingivalis chez un sujet, le procédé comportant l'administration au sujet d'une composition pharmaceutique comportant un agent inhibiteur d'un polypeptide qui réduit ou inhibe la création d'un biofilm et/ou le développement d'un biofilm. L'invention propose également des compositions utiles dans la prévention, l'inhibition ou le traitement d'une maladie parodontale ou d'une infection par P. gingivalis.

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