Pharmaceutical compositions of alkylsulphonamides 5ht1...

A - Human Necessities – 61 – K

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A61K 31/445 (2006.01) A61K 9/02 (2006.01) A61K 31/00 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2135179

The invention relates to a pharmaceutical composition for rectal administration which comprises a compound which acts as a 5HT1-like receptor agonist in the form of its free base or a physiologically acceptable solvate thereof as active ingredient, together with one or more pharmaceutically acceptable carriers or excipients. Methods for the manufacture of such compositions and for their use in the treatment of cephalic pain are also described.

L'invention se rapporte à une composition pharmaceutique, destinée à une administration rectale, qui comprend, comme principe actif, un composé agissant comme agoniste de récepteur analogue à la sérotonine, sous forme de base libre, ou un solvant physiologiquement acceptable de ce composé, ainsi qu'un ou plusieurs vecteurs ou excipients pharmaceutiquement acceptables. Des procédés de préparation de telles compositions, et leur utilisation dans le traitement de céphalées sont également décrits.

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