Pharmaceutical compositions containing ecotin and homologs...

Details Pharmaceutical compositions containing ecotin and homologs... Pharmaceutical compositions containing ecotin and homologs...

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 38/55 (2006.01) C07K 14/81 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2170030

A potent serine protease inhibitor capable of inhibiting Factor Xa, Factor XIIa, plasma kallikrein, and human leukocyte elastase is provided. The inhibitor is provided in a pharmaceutical composition for treatment of diseases where inhibition of Factor Xa, Factor XIIa, plasma kallikrein, or HLE is indicated.

L'invention se rapporte à un puissant inhibiteur de la sérine-protéase capable d'inhiber le facteur Xa, le facteur XIIa, la kallicréine du plasma et l'élastase des leucocytes humains. L'inhibiteur est introduit dans une composition pharmaceutique en vue de traiter des maladies dans lesquelles l'inhibition du facteur Xa, du facteur XIIa, de la hallicréine du plasma ou de HLE (élastase des leucocytes humains) est conseillée.

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