A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 35/16 (2006.01) A61K 38/36 (2006.01) A61L 2/00 (2006.01) A61L 2/18 (2006.01) C07K 16/06 (2006.01) C12N 7/06 (2006.01)
Patent
CA 2173625
The invention relates to a pharmaceutical preparation comprising a plasma protein wherein said preparation is free of infectious agents as well as essentially free of denaturation products and is obtainable by a method that encompasses the following steps: a) addition of a polyether to a solution comprising the plasma protein, optional lyophilization of the solution; b) inactivation of infectious agents in the presence of the polyether by a physio-chemical or chemical treatment, and c) removal of the polyether.
L'invention concerne une préparation pharmaceutique contenant une protéine plasmatique, qui est exempte d'agents infectieux ainsi que, dans une large mesure de produits de dénaturation. Cette préparation s'obtient selon un procédé comprenant les étapes suivantes: a) addition d'un polyéther à une solution contenant la protéine plasmatique, éventuellement lyophilisation de la solution; b) inactivation des agents infectieux en présence du polyéther par traitement physico-chimique ou chimique, et c) élimination du polyéther.
Barrett Noel
Dorner Friedrich
Eibl Johann
Immuno Aktiengesellschaft
Smart & Biggar
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