Urethane derivative, their preparation and their...

C - Chemistry – Metallurgy – 07 – C

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C07C 271/22 (2006.01) A61K 31/27 (2006.01) C07C 275/06 (2006.01) C07C 275/16 (2006.01)

Patent

CA 2020923

General formula urethane derivatives (see Figure 1) in which R represents a CH2OH, -CHOH-CH3 or (CH2)3-NH-CO-NHY grouping, where Y represents -H or COOR', R' representing a linear or branched alkyl group, possibly non-saturated, with 8 to 24 carbon atoms, or a monocyclic cycloalkyl group replaced by an alkyl, with a total number of carbon atoms of 10 or more, as well as the salts of the formula I compounds, and mixtures of formula I compounds and/or their salts; their preparation and application particularly as moisturizing agents in cosmetic or pharmaceutical mixtures used to treat dry skin.

Dérivés d'uréthanne de formule générale : (voir fig. I) dans laquelle R représente un groupement -CH2OH, -CHOH-CH3 ou -(CH2)3-NH-CO-NHY, Y représentant -H ou COOR', R' représente un groupement alkyle linéaire ou ramifié, éventuellement insaturé, ayant de 8 à 24 atomes de carbone, ou un groupement cycloalkyle monocyclique substitué par un alkyle, dont le nombre total des atomes de carbone est supérieur ou égal à 10, ainsi que les sels des composés de formule I, et les mélanges des composés de formule I et/ou de leurs sels ; leur préparation et leur application notamment comme agents hydratants dans des compositions cosmétiques ou pharmaceutiques destinées au traitement des peaux sèches.

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