Glycopeptide derivatives, a process for their preparation...

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 9/00 (2006.01) A61K 38/14 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2091024

Abstract of the disclosure 92/B 005-Ma 935 Glycopeptide derivatives, a process for their preparation and pharmaceutical agents containing these compounds N-Glycopeptide derivatives of the formula I Image formula I where aromatic is an unsubstituted or substituted benzene residue, naphthalene residue, chroman residue, chromene residue or coumarone residue, a is 0 to 5, b is 0 to 4, c is 0 or 1, d is 1 or 2 R1 is (C1-C3)-alkyl, R2 is (C1-C3)-alkyl or (C1-C3)-alkyloxy, R3 is H, OH, (C1-C3)-alkyloxy, NH2, NH-(C1-C6)-alkanoyl, NH-benzoyl, NH-SO3H or NH-acyl radical of a natural N-acetylated amino acid, R4 is H, OH, or (C1-C3)-alkyloxy, R5 is H, OH, (C1-C3)-alkyloxy, fluorine, chlorine or bromine, R6 is H, CH3, CH2OH, CH2O-(C1-C6)-alkanoyl, CH2NHCOCH3 or CH2NH-SO3H, R5 and R6 are together O-CH2-O-CH2, O-CH(CH3)-O-CH2 or O-C(CH3)2-O-CH2, R7 is hydroxy-(C2-C4)-alkyl or (C2-C4)-alkyloxy-(C2-C4)-alkyl, R8 is H or (C1-C6)-alkyl or R7-N-R8 are together a pyrrolidine ring, piperidine ringor morpholine ring, which can be substituted by HO, HOCH2, CH3 or COOH, W -O-, -CONH- or-C6H4-CONH and H-X is HCI, a (C1-C7)-alkanoic acid or another pharmacologically tolerated inorganic or organic acid, are described, as are a process for their preparation and a pharmaceutical agentwhich contains these novel compounds. These pharmaceuticals can be used in particular for the therapy of thrombotic disorders.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Glycopeptide derivatives, a process for their preparation... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Glycopeptide derivatives, a process for their preparation..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glycopeptide derivatives, a process for their preparation... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1596915

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.