Use of an .alpha.-tocopherol phosphate or a derivative...

A - Human Necessities – 61 – K

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A61K 31/665 (2006.01) A61K 8/14 (2006.01) A61K 8/67 (2006.01) A61K 8/97 (2006.01) A61K 9/127 (2006.01) A61K 31/355 (2006.01) A61Q 1/02 (2006.01) A61Q 17/00 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2075201

The present invention relates to the use of an a-tocopherol phosphate, especially in its d1 or d form, or an ester thereof, of the general formula (see formula I) in which: R1 is a hydrogen atom, an alkyl radical having from 1 to 4 carbon atoms, such as the methyl or ethyl radical. in particular, or an a-tocopheryl radi- cal; and R2 is a hydrogen atom, an alkyl radical having from 1 to 4 carbon atoms, such as a methyl or ethyl radical in particular, or an oxyethylene chain of the formula (see formula II) in which R3 and R4 independently are a hydrogen atom or a methyl radical and n is an integer greater than or equal to 1, or a salt thereof, for preparing a pharma- ceutical, dermatological or cosmetic composition for the prevention or treatment of allergic manifestations such as skin allergy or bronchial asthma, or inflamma- tory manifestations, or for the prevention or treatment of the harmful effects of free radicals.

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