Potentiation of autoimmune and inflammatory disease...

Details Potentiation of autoimmune and inflammatory disease... Potentiation of autoimmune and inflammatory disease...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2762206

The invention provides the use of immune regulatory oligonucleotides (IRO) as antagonist of TLRs and potentiators of anti-inflammatory agents that inhibit TNF for the prevention and treatment of inflammatory and autoimmune diseases.

L'invention porte sur l'utilisation d'oligonucléotides régulateurs immuns (IRO) en tant qu'antagonistes des récepteurs Toll (TLR) et potentialisateurs d'agents anti-inflammatoires qui inhibent TNF pour la prévention et le traitement de maladies inflammatoires et auto-immunes.

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