Methods for the production of n-butanol

Details Methods for the production of n-butanol Methods for the production of n-butanol

C - Chemistry, Metallurgy

12

N

C12N 1/21 (2006.01) C12N 1/19 (2006.01) C12N 9/00 (2006.01) C12N 9/04 (2006.01) C12N 9/10 (2006.01) C12N 9/88 (2006.01) C12N 15/09 (2006.01) C12N 15/52 (2006.01) C12P 7/16 (2006.01)

Patent

CA 2703191

Embodiments of the present invention include methods for the production of four carbon alcohols, specifically n-butanol, by a consolidated bioprocessing approach for the conversion of cellulosic material to the desired end product. According to some embodiments, recombinant microbial host cells are provided, preferably S. cerevisiae, that are capable of converting cellulosic material to butanol and include butanol biosynthetic pathway genes and cellulase genes.

dans divers modes de réalisation, l'invention concerne des procédés d'obtention d'alcools à quatre atomes de carbone, en particulier du n-butanol par un procédé de biotraitement consolidé conduisant à la transformation d'un matériau cellulosique en un produit final recherché. Selon certains modes de réalisation, on utilise des cellules hôtes microbiennes recombinantes, de préférence S. cerevisiae, qui sont capables de transformer un matériau cellulosique en butanol et qui conprennent des gènes à voie biosynthétique et des gènes de cellulase.

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