Method of estimating rate of nicotine metabolism in individuals

Details Method of estimating rate of nicotine metabolism in individuals Method of estimating rate of nicotine metabolism in individuals

G - Physics

01

N

G01N 33/94 (2006.01) G01N 33/487 (2006.01) G01N 33/53 (2006.01) G01N 30/02 (2006.01)

Patent

CA 2296963

A simple screening method is provided for determining biological variations among individuals in a smoking cessation program so that a therapy regimen can be adjusted appropriately for each individual. The method includes the steps of having an individual intake a predetermined dose of nicotine, taking a saliva sample at a predetermined time subsequent to intake of the dose of nicotine, and measuring the nicotine and cotinine levels in the sample. Thereafter, a ratio is calculated which includes both the nicotine and cotinine levels as an indicator of the rate of nicotine metabolism of the individual being screened.

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