A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61K 38/43 (2006.01) A61K 38/46 (2006.01) A61K 39/395 (2006.01) A61P 31/12 (2006.01) A61P 31/18 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2515368
Methods of reducing food intake and glucose production in a mammal, or restoring hepatic autoregulation are provided. The methods involve increasing long-chain fatty acyl-Co-A (LC-CoA) levels in the hypothalamus, or stimulating efferent fibers in the hepatic branch of the vagus nerve. Also provided are methods of increasing food intake and glucose production in a mammal. The methods involve decreasing long-chain fatty acyl-Co-A (LC-CoA) levels in the hypothalamus of the mammal.
La présente invention concerne des techniques de réduction de la prise alimentaire et de la production de glucose chez un mammifère ou restauration de l'autorégulation hépatique. Ces techniques consistent à augmenter les niveaux d'acyl-coa gras de chaîne longue (LC-CoA) dans l'hypothalamus ou à stimuler les fibres efférentes dans la ramification hépatique du nerf vague. Cette invention concerne aussi des techniques permettant d'augmenter la prise alimentaire et la production de glucose chez un mammifère. Ces techniques consistent à diminuer les niveaux d'acyl-coa gras de chaîne longue (LC-CoA) dans l'hypothalamus de ce mammifère.
Obici Silvana
Rossetti Luciano
Albert Einstein College Of Medicine Of Yeshiva University
Sim & Mcburney
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