Substituted benzazocines as nicotine-binding inhibitors

Details Substituted benzazocines as nicotine-binding inhibitors Substituted benzazocines as nicotine-binding inhibitors

C - Chemistry, Metallurgy

07

D

C07D 221/22 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2330576

Compounds of formula (I) and their pharmaceutically acceptable salts, wherein R1, R2, R3 and Z are defined as in the specification, intermediates in the synthesis of such compounds, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of neurological and psychological disorders are claimed.

L'invention concerne des composés de formule (I) et leurs sels pharmaceutiquement acceptables dans laquelle R?1¿, R?2¿, R?3¿ et Z sont tels que définis dans l'invention, des intermédiaires dans la synthèse de ces composés, des compositions pharmaceutiques renfermant ces composés et des procédés d'utilisation de ces composés dans le traitement de troubles neurologiques et psychologiques.

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