C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 493/04 (2006.01) A61K 31/4155 (2006.01) A61K 31/428 (2006.01) A61K 31/52 (2006.01)
Patent
CA 2628227
A highly active synthetic epothilone compound whose activity exceeds that of either epothilone EpoA or EpoB when assayed as a cytotoxic agent against a cancer cell line is disclosed as is a pharmaceutical composition containing the synthetic epothilone.
La présente invention a trait à un composé à base d'épothilone de synthèse très actif dont l'activité est supérieure à celle de l'EpoA ou l'EpoB lorsqu'il est soumis à un dosage sous la forme d'un agent cytotoxique contre une lignée cellulaire cancéreuse ainsi qu'à une composition pharmaceutique contenant l'épothilone de synthèse.
Arseniyadis Stellios
Nicolaou Kyriacos C.
Pratt Benjamin
Heenan Blaikie Llp
The Scripps Research Institute
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