Desaturase genes and uses thereof

Details Desaturase genes and uses thereof Desaturase genes and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) A01H 5/00 (2006.01) A61K 31/20 (2006.01) C12N 9/02 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/82 (2006.01) C12P 7/64 (2006.01)

Patent

CA 2698579

The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., .DELTA.5-desaturase") and at carbon 6 (i.e., ".DELTA.6-desaturase") and to uses thereof. In particular, ..DELTA.5-desaturase may be utilized, for example, in the conversion of dihomo-g-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20: 4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to g-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.

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