Synthesis of 1-alpha-hydroxy-secosterol compounds

Details Synthesis of 1-alpha-hydroxy-secosterol compounds Synthesis of 1-alpha-hydroxy-secosterol compounds

C - Chemistry, Metallurgy

07

C

C07C 401/00 (2006.01)

Patent

CA 2062520

This invention provides a new method of making secosterol compounds, and in particular to the preparation of 1.alpha.-hydroxy- homopregnacalciferol which is a secosterol compound that is effective in inducing the differentiation of malignant cells and is therefore useful for the treatment of malignancies such as leukemia.

Le présent brevet porte sur une nouvelle méthode d'obtention de composés à base de sécostérol, et en particulier d'obtention de 1.alpha.-hydroxy-homoprégnacalciférol qui est un composé à base de sécostérol efficace pour induire la différentiation de cellules malignes et est dont utile dans le traitement de cancers comme la leucémie.

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