Recombinant poxvirus comprising at least two cowpox ati...

Details Recombinant poxvirus comprising at least two cowpox ati... Recombinant poxvirus comprising at least two cowpox ati...

C - Chemistry, Metallurgy

12

N

C12N 15/863 (2006.01) A61K 39/275 (2006.01) A61K 39/285 (2006.01) C12N 5/10 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2501168

The invention concerns recombinant poxviruses comprising in the viral genome at least two expression cassettes, each comprising the cowpox ATI promoter or a derivative thereof and a coding sequence, wherein the expression of the coding sequence is regulated by said promoter. The virus may be useful as a vaccine or as part of a pharmaceutical composition.

L'invention concerne des poxvirus de recombinaison renfermant dans le génome viral au moins deux cassettes d'expression, qui contiennent chacune le promoteur ATI de la vaccine ou un dérivé correspondant et une séquence de codage, sachant que l'expression de la séquence de codage est régulée par ledit promoteur. Ce type de virus peut être utile comme vaccin ou comme élément constitutif de composition pharmaceutique.

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