A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/496 (2006.01) A61K 31/341 (2006.01) A61K 31/427 (2006.01) A61K 31/4418 (2006.01) A61K 31/4433 (2006.01) A61K 31/4706 (2006.01) A61K 31/4709 (2006.01) A61K 31/472 (2006.01) A61K 31/4725 (2006.01) A61K 31/513 (2006.01) A61K 31/635 (2006.01) A61K 31/665 (2006.01) A61P 31/18 (2006.01) A61P 33/06 (2006.01)
Patent
CA 2516642
The present invention relates to a drug combination capable of conferring therapeutic benefits in the treatment of both AIDS and malaria. In particular, it relates to a drug combination including at least one quinolinic antimalarial compound such as chloroquine or hydroxychloroquine, and at least one inhibitor of the Human Immunodeficiency Virus (HIV) protease enzyme. This drug combination is capable of inhibiting the replication of both HIV and Plasmodium sp. It also relates to the direct antimalarial effects of the HIV PIs.
La présente invention a trait à une combinaison de médicaments capable de procurer des bienfaits thérapeutiques dans le traitement du SIDA et du paludisme. En particulier, l'invention a trait à une combinaison de médicaments comportant au moins un composé antipaludique de quinoléine tel que la chloroquine ou l'hydroxychloroquine, et au moins une enzyme protéase du virus de l'immunodéficience humaine (VIH). Cette combinaison de médicaments est capable d'inhiber la réplication de VIH et de Plasmodium sp. L'invention a également trait aux effets antipaludiques directs de protéases du VIH
Savarino Andrea
Jarrow Formulas Inc.
Ridout & Maybee Llp
LandOfFree
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