Vascular endothelial cell growth factor antagonists and uses...

Details Vascular endothelial cell growth factor antagonists and uses... Vascular endothelial cell growth factor antagonists and uses...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 38/17 (2006.01) A61P 7/10 (2006.01) C07K 14/71 (2006.01) C07K 16/24 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2355976

The present invention provides vascular endothelial cell growth factor (VEGF) antagonists and methods of using VEGF antagonists. VEGF antagonists contemplated by the invention include VEGF antibodies and VEGF receptor fusion proteins. Methods of treating edema and stroke using VEGF antagonists are also provided.

La présente invention concerne des antagonistes du facteur de croissance endothéliale (VEGF), ainsi que des méthodes d'utilisation de ces antagonistes du VEGF. Les antagonistes du VEGF de cette invention comprennent des anticorps du VEGF et des protéines de fusion du récepteur du VEGF. L'invention concerne enfin des méthodes de traitement des oedèmes et des accidents vasculaires cérébraux s'appuyant sur l'utilisation desdits antagonistes du VEGF.

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