C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/15 (2006.01) A61K 31/18 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2559047
The invention provides N-substituted benzenesulfonamides for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. Compounds of particular interest are defined by Formula (I), wherein R1, R2, R3, R4, and R3, are as described in the specification. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of treating cognitive disorders, including Alzheimer's disease using compounds of Formula (I).
La présente invention a trait à des benzène sulfonamides N-substitués destinés à être utilisés dans le traitement ou la prévention de troubles cognitifs, tels que la maladie d'Alzheimer. Les composés d'intérêt particulier sont définis par la formule (I), dans laquelle : R¿1?, R¿2?, R¿3?, R¿4?, et R¿3?, sont tels que définis dans la description. L'invention a également trait à des compositions pharmaceutiques comportant des composés de formule (I) ainsi qu'à des procédés de traitement de troubles cognitifs, comprenant la maladie d'Alzheimer mettant en oeuvre les composés de formule (I).
Marugg Jennifer
Neitzel Martin
Elan Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
LandOfFree
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