Pyrimidine-4,6-dicarboxylic acid diamides, processes for...

Details Pyrimidine-4,6-dicarboxylic acid diamides, processes for... Pyrimidine-4,6-dicarboxylic acid diamides, processes for...

C - Chemistry, Metallurgy

07

D

167/211, 260/251

C07D 239/28 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07D 403/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2025799

- 1 - HOE 89/F 310 Abstract of the disclosure: Pyrimidine-4,6-dicarboxylic acid diamides, processes for their preparation and the use thereof, and pharmaceuti- cals based on these compounds The invention relates to pyrimidine-4,6-dicarboxylic acid diamides of the formula I Image (I) in which R1 and R2 have the meanings given. The compounds according to the invention inhibit proline hydroxylase and lysine hydroxylase and can be employed as fibro- suppressants and immunosuppressants.

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