Compositions comprising human embryonic stem cells and their...

A - Human Necessities – 61 – K

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Details

IPC codes

A61K 35/48 (2006.01) A61K 35/12 (2006.01) A61P 25/00 (2006.01) C12N 5/06 (2006.01)

Type

Patent

Patent number

CA 2644922

Description

The present invention relates to a pharmaceutical composition comprising of preparations of human embryonic stem (hES) cells and their derivatives and methods for their transplantation into the human body, wherein transplantation results in the clinical reversal of symptoms, cure, stabilization or arrest of degeneration of a wide variety of presently incurable and terminal medical conditions, diseases and disorders. The invention further relates to novel processes of preparing novel stem cell lines which are free of animal products, feeder cells, growth factors, leukaemia inhibitory factor, supplementary mineral combinations, amino acid supplements, vitamin supplements, fibroblast growth factor, membrane associated steel factor, soluble steel factor and conditioned media. This invention further relates to the isolation, culture, maintenance, expansion, differentiation, storage, and preservation of such stem cells.

La présente invention concerne une composition pharmaceutique qui comprend des préparations de cellules souches embryonnaires humaines (human Embryonic Stem; hES) et leurs dérivés, ainsi que des procédés permettant de les transplanter dans un organisme humain dans lequel la transplantation se traduit par l'inversion clinique des symptômes, la guérison, la stabilisation ou l'arrêt de la dégénérescence d'une grande diversité d'états médicaux, de maladies et d'affections actuellement incurables et mortels. L'invention concerne également des procédés innovants de préparation de lignées de cellules souches innovantes exemptes de produits animaux, de cellules nourricières, de facteurs de croissance, de facteur inhibiteur de la leucémie, de combinaisons de minéraux complémentaires, de suppléments d'acides aminés, de suppléments vitaminés, de facteur de croissance des fibroblastes, de facteur Steel associé à la membrane, de facteur Steel soluble et de milieu conditionné. La présente invention concerne en outre l'isolement, la culture, l'entretien, l'expansion, la différenciation, le stockage et la conservation de telles cellules souches.

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