Water soluble fluorinated fatty acid sulfonate derivatives...

Details Water soluble fluorinated fatty acid sulfonate derivatives... Water soluble fluorinated fatty acid sulfonate derivatives...

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61B 5/055 (2006.01) A61K 49/06 (2006.01)

Patent

CA 2217390

The present invention relates to improved imaging agents useful for 19F magnetic resonance imaging (MRI). More particularly, the present invention relates to fluorinated fatty acid sulfonate derivatives, such as those derived by reaction of fluorinated fatty acids with sulfonated compounds such as taurine analogs or isethionic acid analogs, which offer improved water solubility and biocompatibility.

Agents d'imagerie utiles pour l'imagerie par résonance magnétique (IRM) au ?19¿F. Plus particulièrement, l'invention concerne des dérivés de sulfonates d'acide gras fluorés, tels que ceux dérivés par réaction d'acides gras fluorés avec des composés sulfonatés tels que des analogues de taurine ou des analogues d'acides iséthioniques, qui améliorent l'hydrosolubilité et la biocompatibilité.

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