Method and composition for prolonging the residence time of...

A - Human Necessities – 61 – K

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A61K 47/26 (2006.01) A61K 9/00 (2006.01) A61K 9/48 (2006.01) A61K 45/00 (2006.01) A61K 47/22 (2006.01) A61K 47/24 (2006.01)

Patent

CA 2451360

The present invention provides methods and compositions for slowing the transit time of pharmaceutical compounds, nutritional supplements, and vitamins through the gastrointestinal tract, prolonging residence time of such compounds, and thereby increasing absorption in the small intestine, by utilizing the cellular regulatory compound cyclic GMP. The present invention also provides methods and compositions for enhancing the bioavailability and therapeutic effectiveness of pharmacologically active agents, vitamins, and nutritional supplements.

La présente invention concerne des méthodes et des compositions permettant de ralentir le temps de transit de composés pharmaceutiques, de compléments nutritionnels et de vitamines à travers le tractus gastro-intestinal, de prolonger le temps de séjour de ces composés et d'augmenter, ainsi, leur absorption dans l'intestin grêle, en utilisant le GMP cyclique en tant que composé de régulation cellulaire. Ladite invention concerne également des méthodes et des compositions permettant d'augmenter la biodisponibilité et l'efficacité thérapeutique d'agents pharmacologiquement actifs, de vitamines et de compléments nutritionnels.

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