Sulfonamide-substituted benzopyran derivatives, processes...

C - Chemistry – Metallurgy – 07 – D

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C07D 311/70 (2006.01) A61K 31/35 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 311/68 (2006.01) C07D 311/72 (2006.01) C07D 311/96 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 417/00 (2006.01)

Patent

CA 2252733

Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as a medicament, and pharmaceutical preparations comprising them Compounds of the formula I (see fig. I) having the meanings of the substituents indicated in the claims are outstandingly active substances for the production of medicaments for the prophylaxis and for the therapy of cardiovascular disorders, in particular arrhythmias, for the treatment of ulcers of the gastrointestinal region or for the treatment of diarrheal diseases.

Divulgation de dérivés du benzopyrane substitué par un sulfonamide, de procédés de préparation de ces dérivés, de leur utilisation comme médicament et de préparations pharmaceutiques à base de ces dérivés. Des composés de la formule I (voir fig. I) ayant les significations des substituants indiqués dans les revendications sont des principes remarquablement actifs pour la production de médicaments servant à prévenir et à traiter les troubles cardiovasculaires, en particulier l'arythmie, et à traiter les ulcères gastro-intestinaux ou les maladies diarrhéiques.

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