Parathyroid hormone derivatives and their use

Details Parathyroid hormone derivatives and their use Parathyroid hormone derivatives and their use

C - Chemistry, Metallurgy

07

K

C07K 14/635 (2006.01) A61K 38/29 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2178894

Disclosed is a parathyroid hormone (PTH) (1-34) derivative in which at least the amino acid residue at the 10-position is substituted by an acidic amino acid residue. The derivatives of the present invention showing potent cAMP-producing activity and bone formation activity, and thus are useful as therapeutic agents for bone diseases, etc.

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