Use of cyclolignans for the treatment of a hyperactive...

A - Human Necessities – 61 – K

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A61K 31/365 (2006.01) A61K 31/36 (2006.01) A61P 11/06 (2006.01) A61P 25/28 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2728652

There is disclosed use of certain picro derivatives of cyclolignans for prophylaxis or treatment of diseases or conditions characterised by a hyperac-tive immune system. Examples of cy-clolignans according to the invention include picropodophyllin, deoxypicrop-odophyllin, anhydropicropodophyllol or deoxyanhydropicropodophyllol. Formula (I)

La présente invention a pour objet lutilisation de certains dérivés picro de cyclolignanes pour la prophylaxie ou le traitement de maladies ou daffections caractérisées par un système immunitaire hyperactif. Les exemples de cyclolignanes selon linvention comprennent la picropodophylline, la désoxypicropodophylline, lanhydropicropodophyllol ou le désoxyanhydropicropodophyllol.

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