Valproic acid drug delivery systems and intraocular...

Details Valproic acid drug delivery systems and intraocular... Valproic acid drug delivery systems and intraocular...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 31/19 (2006.01)

Patent

CA 2752206

Biocompatible, bioerodible, sustained release drug delivery system formulated as implants, microspheres and high viscosity hyaluronic acid solutions comprise valproic acid as therapeutic agent and a biodegradable polymer, the system being effective, when placed intraocular (such as into the subtenon space or into the vitreous) to treat a retinal disease or condition.

L'invention porte sur un système d'administration de médicament à administration entretenue, bioérodable, biocompatible, formulé sous la forme d'implants, de microsphères et de solutions d'acide hyaluronique à viscosité élevée, comprenant de l'acide valproïque en tant qu'agent thérapeutique et un polymère biodégradable, le système étant efficace lorsqu'il est placé de façon intraoculaire (tel que dans l'espace sous-épiscéral ou dans le corps vitré) pour traiter une maladie rétinienne ou un état rétinien.

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