C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/94 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 209/64 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2117164
Abstract Tetrahydrocyclopent[b]indole methanamines and related compounds, a process for their preparation and their use as medicaments There are disclosed various compounds of the formula below, Image where the various parameters R1, R2, R3, R4, X, m and n are as defined in the specification, which show activities as a monoamine oxidase inhibitor demonstrating a utility for the treatment of depression, and activities as a cholinesterase inhibitor demonstrating a utility for the treatment of various memory dysfunctions such asAlzheimer's disease.
Davis Larry
Martin Lawrence Leo
Aventis Pharmaceuticals Inc.
Bereskin & Parr
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