C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/415 (2006.01) A01H 5/10 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) C12N 15/82 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2528845
The present invention describes novel polypeptide structures based on oleosin molecules which are capable of being targeted to oil bodies in plants. The modified oleosin polypeptides are obtained by performing modifications in the hydrophobic domain encoding sequence of an oleosin cDNA. The present invention describes methods to obtain such polypeptides in vivo. The novel oleosins may be used to deliver a recombinant (non-oleosin) protein to oil bodies.
La présente invention concerne de nouvelles structures polypeptidiques à base de molécules d'oléosine capables d'être la cible de corps lipidiques chez les plantes. Ces polypeptides d'oléosines modifiées sont obtenus à l'aide d'une technique consistant à réaliser des modification dans la séquence codant pour le domaine hydrophobe d'un ADNc d'oléosine. La présente invention concerne également des procédés permettant d'obtenir ces polypeptides in vivo. Ces nouvelles oléosines peuvent être utilisées pour fournir une protéine recombinée (non oléosine) aux corps lipidiques.
Moloney Maurice M.
Siloto Rodrigo Marins
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sembiosys Genetics Inc.
Uti Limited Partnership
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