Substituted quinolines

Details Substituted quinolines Substituted quinolines

C - Chemistry, Metallurgy

07

D

C07D 215/14 (2006.01) A61K 31/47 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2064015

2064015 9103466 PCTABS00003 The present invention relates to hitherto unknown compounds of formula (I), in which m and n stand for an integer from 0-5, p stands for 0 or 1, and q stands for an integer from 0-4, R1 and R2 are the same or different and stand for hydrogen, halogen, nitro, amino, alkyl or alkoxy; R3 is hydroxy, hydrogen, straight or branched, saturated or unsaturated C1-C6 alkyl; R5 stands for an acidic group, e.g. carboxy, 1-H tetrazolyl, a sulphonic acid group, a sulfamyl group, a sulphinic acid group, or a hydroxamic acid group; R4 and R6 are the same or different and stand for hydrogen, straight or branched, saturated or unsaturated, unsubstituted or substituted C1-C6 alkyl groups or unsubstituted or substituted aralkyl groups. R7 has the same meaning as R5 or represents a hydrogen, straight or branched, saturated or unsaturated, unsubstituted or substituted C1-C6-alkyl group. The present compounds are of value in the human and veterinary practice as lipoxygenase inhibitors and/or leukotriene antagonists.

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