Ginsenoside chemotherapy

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/70 (2006.01) A61K 31/135 (2006.01) A61K 31/335 (2006.01) A61K 35/78 (2000.01)

Patent

CA 2407792

The invention provides for the use of ginsenoside Rh2 in pharmaceutical compositions used in methods of inhibiting the multiplication of cancer cells, and methods of treating cancer in patients, comprising administering to such patients therapeutically and synergistically effective amounts of Rh2 in combination with a chemotherapeutic selected from the group consisting of paclitaxel and mitoxantrone. The cancer cells to be treated may be multidrug resistant. The cancer cells may for example be prostate cancer cells or breast cancer cells.

L'invention concerne l'utilisation de ginsenoside Rh2 dans des compositions pharmaceutiques utilisées dans des procédés servant à empêcher la multiplication de cellules cancéreuses, et des procédés servant à traiter le cancer chez des patients, qui comprennent l'administration à ces patients de quantités efficaces thérapeutiquement et au niveau de la synergie de Rh2 en combinaison avec une substance chimiothérapeutique sélectionnée dans le groupe comprenant le paclitaxel et le mitoxantrone. Les cellules cancéreuses à traiter peuvent être résistantes à de multiples médicaments. Les cellules cancéreuses peuvent être par exemple des cellules du cancer de la prostate ou des cellules du cancer du sein.

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