A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/135 (2006.01) A61K 31/52 (2006.01) A61K 31/522 (2006.01) A61K 31/138 (2006.01)
Patent
CA 2340427
Disclosed are N-substituted metabolites of diphenhydramine, which have been found to be potent and orally active antihistaminic compounds that are devoid of sedative side effects. Pharmaceutically acceptable salts of the compounds, a complex with 8-chlorotheo- phylline, therapeutic use and compositions containing the compounds are also described.
L'invention concerne des métabolites, à substitution en N, de diphénhydramine, lesquels constituent des composés antihistaminiques puissants, actifs par voie orale, et dépourvus d'effets secondaires sédatifs. L'invention concerne également des sels de ces composés, acceptables sur le plan pharmacologique, un complexe avec la 8-chlorothéophylline, ainsi que l'utilisation thérapeutique des ces composés et des compositions les contenant.
Bridge Pharma Inc.
Deeth Williams Wall Llp
LandOfFree
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