Process for the preparation of 13c-labelled compounds

Details Process for the preparation of 13c-labelled compounds Process for the preparation of 13c-labelled compounds

C - Chemistry, Metallurgy

12

P

C12P 19/24 (2006.01) C12N 11/18 (2006.01) C12P 1/00 (2006.01) C12P 19/02 (2006.01) C12P 19/14 (2006.01)

Patent

CA 2062453

A process for preparing a 13C-labelled compound which comprises reacting an alcohol 13C-labelled carbon source compound and a substrate in the presence of an enzyme system consisting of oxidase belonging to EC1 group and capable of converting the alcohol 13C-labelled carbon source compound to an aldehyde 13C-labelled carbon source compound, lyase belonging to EC4 group and capable of synthesizing a carbon-carbon bond and at least one of isomerases belonging to EC5 group and capable of isomerizing substrates to obtain a 13C-labelled compound specifically labelled with 13C in a specific carbon position.

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