Membrane-permeable inhibitor of dynamin-mediated endocytosis

Details Membrane-permeable inhibitor of dynamin-mediated endocytosis Membrane-permeable inhibitor of dynamin-mediated endocytosis

A - Human Necessities

61

K

A61K 9/00 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2333751

Disclosed is a membrane permeable molecule which inhibits dynamin-mediated endocytosis in an eukaryotic cell, the molecule comprising a membrane permeable hydrophobic moiety, and a peptide moiety comprising the amino acid sequence QVPSRPNRAP.

L'invention concerne une molécule à perméabilité membranaire destinée à inhiber, dans une cellule eucaryote, une endocytose ayant pour origine la dynamine, cette molécule renfermant un fragment hydrophobe à perméabilité membranaire et un fragment peptidique renfermant la séquence aminoacide QVPSRPNRAP.

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